History 30B, Spring 2000

Science and Society since the Scientific Revolution

Daily outline, Class 28 (4/27/00)

Guest lecture by Prof. Nick Rasmussen
 

Topics 

Genetic engineering, eugenics, and molecular genetics

The Rockefeller Foundation

Prehistory:  basic science and social control
Depression-era reorientation:  vital processes
Sustaining biophysics

The effects of World War II

Appreciation of basic science
National health care or medical research

Biophysics in the early postwar years

Bacterial viruses
Structural biophysics, x-ray crystallography of proteins
DNA and the genetic code

The origins of genetic engineering

Bacterial genetics
Recombinant DNA techniques
Safety concerns
The market

Names and terms   

Hermann J. Muller
John D. Rockefeller
Rockefeller Foundation (founded 1913)
Warren Weaver
Jacques Loeb, general physiology
ultracentrifuge, electrophoresis apparatus, electron microscope, x-ray diffraction
National Science Foundation (founded 1950)
National Institutes of Health (founded 1930)
Office of Naval Research, Atomic Energy Commission
bacterial virus / (bacterio)phage
Max Delbrück (1906-1981)
James Watson (b. 1928) and Francis Crick (b. 1916)
DNA (deoxyribonucleic acid), RNA (ribonucleic acid)
plasmid
gene regulation
host-range restriction
restriction enzyme
DNA polymerase, ligase
Asilomar (1975)
Genentech (founded 1976)
initial public offering
Chakrabarty decision, Bayh-Dole Act

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